Research / Publications
Publications & Presentations
Biopathio's scientific output to date includes preprints and conference presentations. As a 2024-founded preclinical company, these represent our early-stage formulation and mechanism work.
Note: This list reflects early-stage scientific work including preprints and conference presentations. Formal peer review is ongoing for selected studies. Publication dates are 2024–2025, consistent with our founding year.
2025
Preprint
Dual-Cargo CRISPR LNP Formulation for Base Editor Delivery in Primary Cortical Neurons
bioRxiv preprint. February 2025. doi: 10.1101/2025.02.14.580211 [synthetic identifier]
Conference Poster
Expanded Characterization Panel for CNS-Targeted LNPs: Beyond DLS and Encapsulation Efficiency
Gordon Research Conference on Drug Carriers in Medicine and Biology. Ventura, CA. March 2025.
2024
Preprint
Ionizable Lipid pKa Optimization for CNS-Targeted Nanoparticle Delivery Across the Blood-Brain Barrier
bioRxiv preprint. September 2024. doi: 10.1101/2024.09.03.611087 [synthetic identifier]
Conference Poster
Receptor-Mediated BBB Transcytosis of Engineered Lipid Nanoparticles: In Vitro Evidence in hCMEC/D3 Models
American Society of Gene and Cell Therapy (ASGCT) Annual Meeting. Baltimore, MD. May 2024.
Invited Seminar
The BBB Delivery Gap in CRISPR CNS Therapy: How Ionizable LNPs Can Bridge It
Department of Pharmaceutics, College of Pharmacy, University of Minnesota. Minneapolis, MN. November 2024.
Questions about our research or collaboration opportunities?
We are open to scientific discussion with researchers working on CNS gene therapy delivery.